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UNIO’08 2.0.2

UNIO enables protein structure determination within one week



UNIO’08 2.0.2 facilities

Vendor`s Webhttp://www.ens-lyon.fr
Centre Européen de RMN à Très Hauts Champs webshot
OSMac OS, Linux
Limitationsnot specified
Actualizedmore than year ago

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UNIO’08 manufacturer description

UNIO enables you to perform automated NMR data analysis for protein 3D structure determination. UNIO NMR data analysis interconnects the MATCH algorithm for backbone assignment (1), the ASCAN algorithm for side-chain assignment (2) and the CANDID algorithm for NOE assignment (3). The ATNOS algorithm for robust signal identification in NMR spectra is employed to grant each of the three expert-systems direct access to the raw NMR data (4), thus enabling integrated and consistent data evaluation. The UNIO data analysis protocol requires only a minimal set of 3-6 NMR spectra, namely APSY and NOESY, and features high computational efficiency. The experience gained so far shows that the UNIO approach leads to objective and consistent NMR data interpretation (see UNIO structures).
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